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Weedguru Higher
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Post by Weedguru Higher » Tue Apr 13, 2010 10:46 am



Gamma-hydroxy-butyrate or GHB, as it is known on the street, is a clear liquid (it is also available in powder form, but rarely seen). The substance itself is colorless, odorless and nearly tasteless. While GHB is found naturally in the brain and other tissues in very small quantities, synthetic GHB is manufactured from its precursor, gamma-butyrolactone (also known as GBL), which is a solvent, found in floor cleaning products, nail polish and super glue removers.


Developed in 1961 by renowned French researcher Dr. Henri Laborit, GHB was originally developed as an anesthetic, but was soon withdrawn due to unwanted side effects. In the United States GHB was readily available in the 1980's in health food stores. It gained popularity through its use by body builders who thought the drug would increase their body mass and was used much like steroids are used. In 1990 the Federal Drug Administration labeled GHB a "dangerous drug," but did not make it a controlled substance, subject to regulation under the federal Controlled Substance Act.

In the mid to late 1990s GHB acquired a reputation as a date-rape drug and is now in the process of being added to the DEA's list of Schedule I drugs. Most states though, have restrictions on its use and sale. The FDA has revoked its federal approval and has declared it available in the United States only as an investigational new drug for specified purposes (usually scientific study). GBL, though, is still available over-the-counter.


Dosages range from one gram or less, which is considered a mild dose to upwards of five grams in a single dose. GHB is often sold on the street in small bottles, approximately the size of a hotel shampoo bottle. These bottles usually contain about ten doses and a dose is measured as one capful. The powdered form of GHB can also be sniffed.


GHB depresses the respiratory system and reduces the amount of oxygen the brain receives, resulting, with large doses, in unconsciousness and loss of memory. At small doses, GHB encourages a reduction of social inhibitions, similar to alcohol, and an increased libido. At higher doses, this euphoria gives way to feelings of sedation. Reported symptoms include vomiting, drowsiness, dizziness, vertigo, and seizures. After excessive use, some users have experienced loss of consciousness, irregular and depressed respiration, tremors or coma. A number of deaths have occurred from GHB overdoses.
Source: Morbidity and Mortality Weekly Report, 1990 November 30


Physical Dependence: Reported but unconfirmed
Psychological Dependence: Moderate
Tolerance: Moderate


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